This cardiovascular risk panel test may be right for you if any of the following are true:
You want to better understand your risk of a heart attack, heart disease, stroke, and other diseases of the blood vessels
You have identified multiple CVD risk factors, such as:
Age (risk increases with age)
Being overweight or obese
High blood pressure
Lifestyle risk factors (ie, smoking, sedentary lifestyle, poor diet, etc.)
Reproductive health history risk factors (ie, pre-eclampsia, gestational diabetes, PCOS, etc.)
Family history of CVD
You are at risk for or have pre-diabetes/diabetes
You have a history of CVD
This test panel measures the following levels in your blood that are commonly evaluated by healthcare providers to determine risk of heart attack or stroke.
Total cholesterol
—This measures the total amount of cholesterol found in your blood. This is the combination of low-density lipoprotein (LDL, or “bad”) cholesterol and high-density lipoprotein (HDL, or “good”) cholesterol. Too much cholesterol in your blood may damage arteries and blood vessels, which may increase the risk for a stroke, heart attack, and heart disease.
High-density lipoprotein
HDL, which is often called "good" cholesterol, picks up extra cholesterol that is circulating in the blood, using apolipoprotein A, and takes it back to your liver so it can be removed from your body.
Triglycerides
—Triglycerides are fats that are formed from foods such as oils, dairy, and red meat. These fats get converted into triglycerides and are stored away in fat cells to be used when needed. High levels of triglycerides can lead to hardening and thickening of the arteries.
Low-density lipoprotein (LDL) (calculated)
—LDL, often called "bad" cholesterol, transports cholesterol throughout your body to the cells that need it. Too much LDL can make cholesterol build up in your arteries, making them narrow and stiff, or blocking them, which makes it more difficult for blood to flow.
Cholesterol/HDL ratio (calculated)
—Cholesterol/HDL ratio is the ratio of HDL to your total cholesterol. A higher ratio means that you don’t have enough HDL for the amount of LDL, and that can lead to cardiovascular disease.
Non-HDL cholesterol (calculated)
—Non-HDL cholesterol measures the combined amount of cholesterol in the blood that is not HDL cholesterol. High levels of non-HDL cholesterol may increase the risk of atherosclerosis (narrowing of arteries).
Lipoprotein fractionation, ion mobility
—Advanced lipid testing with ion mobility measures the LDL and HDL cholesterol size and amount that is circulating in the blood. A higher number of small LDL particles may increase risk of CVD, heart attack, or stroke, even if traditional LDL cholesterol levels are normal.
Apolipoprotein B
—Apolipoprotein B (ApoB) carries LDL cholesterol and other potentially harmful lipid particles around the body. It includes all cholesterol particles that can form plaque in your arteries and lead to cardiovascular disease. Levels of ApoB can indicate a risk of cardiovascular disease, even if traditional LDL cholesterol levels are normal.
Lipoprotein (a)
—Lipoprotein(a), like LDL, is a low-density lipoprotein that transports cholesterol throughout the body. Too much of it can cause cholesterol to build up in your blood vessels, forming plaques and reducing blood flow to your brain, heart, and other body parts.
hs-CRP
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High-sensitivity CRP (hs-CRP) is more sensitive than a CRP test and accurately detects low but persistent levels of inflammation, which may be associated with developing cardiovascular disease.
Lipoprotein-associated phospholipase A2 activity
—Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an enzyme (active protein) that is a marker of cardiovascular inflammation. Cardiovascular inflammation may suggest you have an “injury” in your body, such as cholesterol buildup. Measuring Lp-PLA2 Activity can identify active plaque in your artery walls that —causes cardiovascular disease. High levels of Lp-PLA2 Activity increase your risk of heart attack and stroke.